Therefore, rosemary products can be a useful functional ingredient for the production of new functional foods. Rosemary leaves, extracts, and essential oil have received recognition as generally recognized as safe (GRAS) for their intended use, from Food and Drug Administration and according to Commission Directive 2010/67/EU and Commission Directive 2010/69/EU. Due to valuable bioactive compounds (BACs), rosemary possess antioxidant, anticancer, diuretic, antimicrobial, antiproliferative, anti-inflammatory, and anti-hyperglycemic properties. The biological activity of rosemary is mostly related to the phenolic compounds, such as carnosol, carnosic acid, and rosmarinic acid, and volatile compounds from essential oil like α-pinene, camphor, eucalyptol, or 1,8-cineole. From ancient times, rosemary has been used as flavoring agent and for medicinal purposes due to its intense aromatic odor and health benefits.
Rosemary ( Rosmarinus officinalis L.) is an autochthonous Mediterranean herb from Lamiaceae family. The computational stimulation methods were confirmed by experimental study, ethanol had higher potential of solubility of BACs and aromas from rosemary compared to water. HVED was confirmed to have a high potential for extraction of BACs from rosemary. Furthermore, nitrogen, longer treatment time and higher voltage enhanced higher yields in HVED extraction. Results showed that HVED extracts in average 2.13-times higher total phenol content compared to CE. The comparison was done with modified conventional extraction (CE) extracted by magnetic stirring and physicochemical analyses of obtained extracts were done. Green solvents were used, water and ethanol (25% and 50%). The optimal HVED parameters were as follows: frequency 100 Hz, pulse width 400 ns, gap between electrodes 15 mm, liquid to solid ratio 50 mL/g, voltage 15 and 20 kV for argon, and 20 and 25 kV for nitrogen gas. The aim of the study was to evaluate the extraction of intracellular compounds from rosemary combining experimental procedure by means of high voltage electrical discharge (HVED), with a theoretical approach using two computational simulation methods: conductor-like screening model for real solvents and Hansen solubility parameters.
Rosemary ( Rosmarinus officinalis L.) is a Mediterranean medicinal and aromatic plant widely used due to valuable bioactive compounds (BACs) and aromas.